what causes recurrent miscarriage

                             RECURRENT MISCARRIAGE


Sometimes people got to wonder why recurrent miscarriage occur and they get to fear when a miscarriage happens unexpected.

 Recurrent miscarriage is defined as the loss of three or more consecutive pregnancies.
This is a problem that affects 1% of all women,and the risk of further abortion increases with each pregnancy lost.

 The incidence of recurrent miscarriage suggests that there are significant underlying causes and the loss of the pregnancy is not chance.

             FACTORS ASSOCIATED WITH RECURRENT MISCARRIAGE



  • Genetic causes. The parental karyotype is abnormal, the most common abnormality is trans location.

  • Immunological factors. women with a history of recurrent pregnancy loss have been found to lack an ig-G blocking agent.In a normal pregnancy    coats the fetal antigens and prevents rejection of the fetus.

  • hyper secretion of Lh: This may act on the oocyte causing it to age or on the endometrium resulting in error in implantation.Mothers with polycystic ovaries have  reduced fertility and an increased risk of early pregnancy loss.

  • infection;The role of infection in recurrent early pregnancy failure is unclear.Alteration of the normal vaginal flora may contribute to recurrent miscarriage when loss or reduced levels of lactobacilli occur with the condition bacterial vaginosis.toxoplasma gondii,listeria and cytomegalovirus are infective agents associated with pregnancy loss

  • structural anomalies:Both uterine abnormalies and cervical incompetence have been attributed as causes of recurrent loss

In many cases no causative factor is identified.Women should be referred to hospitals,where a screening service is available,thus enabling a probable cause to be  identified

















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